Pub. Date : 1994 Aug 17
PMID : 8080435
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | CYP2C11 and CYP2B1 are major cytochrome P450 forms involved in styrene oxidation in liver and lung microsomes from untreated rats, respectively. | Styrene | cytochrome P450, family 2, subfamily b, polypeptide 1 | Rattus norvegicus |
| 2 | These results suggest that (1) at least four P450s, CYP2C11/6, CYP2E1, CYP2B1/2 and CYP1A1/2, contribute to the metabolism of styrene, (2) CYP2C11/6, which probably corresponds to CYP2C11, is the major form of P450 responsible for the metabolism in untreated rat liver microsomes, and also in those treated with ethanol. | Styrene | cytochrome P450, family 2, subfamily b, polypeptide 1 | Rattus norvegicus |
| 3 | Only anti-CYP2B1/2, which probably corresponds to CYP2B1, inhibited styrene oxidation in lung microsomes from untreated and even styrene-treated rats. | Styrene | cytochrome P450, family 2, subfamily b, polypeptide 1 | Rattus norvegicus |
| 4 | Only anti-CYP2B1/2, which probably corresponds to CYP2B1, inhibited styrene oxidation in lung microsomes from untreated and even styrene-treated rats. | Styrene | cytochrome P450, family 2, subfamily b, polypeptide 1 | Rattus norvegicus |
| 5 | Only anti-CYP2B1/2, which probably corresponds to CYP2B1, inhibited styrene oxidation in lung microsomes from untreated and even styrene-treated rats. | Styrene | cytochrome P450, family 2, subfamily b, polypeptide 1 | Rattus norvegicus |
| 6 | Only anti-CYP2B1/2, which probably corresponds to CYP2B1, inhibited styrene oxidation in lung microsomes from untreated and even styrene-treated rats. | Styrene | cytochrome P450, family 2, subfamily b, polypeptide 1 | Rattus norvegicus |