Title : Measurement of liver microsomal cytochrome p450 (CYP2D6) activity using [O-methyl-14C]dextromethorphan.

Pub. Date : 1994 Jun

PMID : 8080088






1 Functional Relationships(s)
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1 Furthermore, the O-demethylase activity in a panel of microsomes prepared from a series of human livers was significantly correlated with the immunochemically determined levels of CYP2D6 protein (r = 0.925, p < 0.001), and was inhibited (> 89%) by quinidine and lobeline. Lobeline cytochrome P450 family 2 subfamily D member 6 Homo sapiens