Pub. Date : 1994 Feb
PMID : 8060496
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Comparison of the low energy conformations of an oncogenic and a non-oncogenic p21 protein, neither of which binds GTP or GDP. | Guanosine Diphosphate | H3 histone pseudogene 16 | Homo sapiens |
| 2 | Since p21 is normally activated by the binding of GTP in place of GDP, it has been postulated that oncogenic forms must retain bound GTP for prolonged time periods. | Guanosine Diphosphate | H3 histone pseudogene 16 | Homo sapiens |
| 3 | However, two multiply substituted p21 proteins have been cloned, neither of which binds GDP or GTP. | Guanosine Diphosphate | H3 histone pseudogene 16 | Homo sapiens |
| 4 | These regions have been found to be the most flexible in the p21 protein bound to GDP from prior molecular dynamics calculations (Dykes et al., 1993). | Guanosine Diphosphate | H3 histone pseudogene 16 | Homo sapiens |