Title : Tumor-induced regulation of suppressor macrophage nitric oxide and TNF-alpha production. Role of tumor-derived IL-10, TGF-beta, and prostaglandin E2.

Pub. Date : 1994 Aug 15

PMID : 8046239






1 Functional Relationships(s)
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1 This tumor-induced increase in Mphi NO and TNF-alpha production mediated suppression of alloantigen-driven T cell proliferation, because treatment with either NG-monomethyl-L-arginine or anti-TNF-alpha Ab blocked tumor-bearing host Mphi-mediated suppression. omega-N-Methylarginine tumor necrosis factor Homo sapiens