Title : Regulation of the GLUT1 glucose transporter in cultured myocytes: total number and subcellular distribution as determined by photoaffinity labelling.

Pub. Date : 1994 Jul 1

PMID : 8037688






2 Functional Relationships(s)
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1 Feeding the cells with glucose (25 mM) for 24 h resulted in an 80% decrease in the total GLUT1 content relative to starved cells, of which only 25% were present on the cell surface. Glucose solute carrier family 2 (facilitated glucose transporter), member 1 Mus musculus
2 This technique demonstrates that glucose pre-feeding (1) decreases the total number of GLUT1 and (2) redistributes the majority of the remaining transporters to an intracellular site, where they can now be translocated to the cell surface in response to insulin and PMA. Glucose solute carrier family 2 (facilitated glucose transporter), member 1 Mus musculus