Pub. Date : 1994 Aug 1
PMID : 8033120
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Immunohistochemical staining of human spermidine/spermine N1-acetyltransferase superinduced in response to treatment with antitumor polyamine analogues. | Polyamines | spermidine/spermine N1-acetyltransferase 1 | Homo sapiens |
| 2 | A superinduction of the polyamine catabolic enzyme, spermidine/spermine N1-acetyltransferase (SSAT) accompanies the phenotype-specific cytotoxic response to a class of antitumor polyamine analogues in several important human solid tumor models. | Polyamines | spermidine/spermine N1-acetyltransferase 1 | Homo sapiens |
| 3 | A superinduction of the polyamine catabolic enzyme, spermidine/spermine N1-acetyltransferase (SSAT) accompanies the phenotype-specific cytotoxic response to a class of antitumor polyamine analogues in several important human solid tumor models. | Polyamines | spermidine/spermine N1-acetyltransferase 1 | Homo sapiens |
| 4 | A superinduction of the polyamine catabolic enzyme, spermidine/spermine N1-acetyltransferase (SSAT) accompanies the phenotype-specific cytotoxic response to a class of antitumor polyamine analogues in several important human solid tumor models. | Polyamines | spermidine/spermine N1-acetyltransferase 1 | Homo sapiens |
| 5 | A superinduction of the polyamine catabolic enzyme, spermidine/spermine N1-acetyltransferase (SSAT) accompanies the phenotype-specific cytotoxic response to a class of antitumor polyamine analogues in several important human solid tumor models. | Polyamines | spermidine/spermine N1-acetyltransferase 1 | Homo sapiens |
| 6 | Using this antiserum we demonstrate that polyamine analogue treatment in vitro or in vivo results in an induction of SSAT protein which is uniformly distributed throughout the cytoplasm of treated tumor cells. | Polyamines | spermidine/spermine N1-acetyltransferase 1 | Homo sapiens |
| 7 | Additionally, since clinical trials have begun on one of the SSAT-inducing polyamine analogues, this antiserum may be useful as a diagnostic tool in differentiating responsive and nonresponsive tumor cell populations in treated patients. | Polyamines | spermidine/spermine N1-acetyltransferase 1 | Homo sapiens |