Title : N-acetylgalactosamine glycosylation of MUC1 tandem repeat peptides by pancreatic tumor cell extracts.

Pub. Date : 1994 Jul 15

PMID : 8033093






2 Functional Relationships(s)
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1 Synthetic peptides corresponding to the human mucin MUC1 tandem repeat domain (20 residues) were glycosylated in vitro by using UDP-N-[3H]acetyl-D-galactosamine (GalNAc) and lysates of pancreatic tumor cell lines. N-acetylgalactosaminuronic acid mucin 1, cell surface associated Homo sapiens
2 The results showed that two of three threonine residues on the MUC1 tandem repeat peptides were glycosylated by pancreatic tumor cell lysates at the following positons: GVTSAPDTRPAPGSTAPPAH (underlined T indicates position of GalNAc attachment). N-acetylgalactosaminuronic acid mucin 1, cell surface associated Homo sapiens