Pub. Date : 1994 Mar
PMID : 8003768
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | An interleukin-1 beta-induced noradrenaline release in the spleen is mediated by brain corticotropin-releasing factor: an in vivo microdialysis study in conscious rats. | Norepinephrine | interleukin 1 beta | Rattus norvegicus |
| 2 | The purpose of this study was to investigate whether an intraperitoneal injection of interleukin-1 beta (IL-1 beta) affects noradrenaline release in the spleen through its action on the brain of conscious rats. | Norepinephrine | interleukin 1 beta | Rattus norvegicus |
| 3 | The purpose of this study was to investigate whether an intraperitoneal injection of interleukin-1 beta (IL-1 beta) affects noradrenaline release in the spleen through its action on the brain of conscious rats. | Norepinephrine | interleukin 1 beta | Rattus norvegicus |
| 4 | The intraperitoneal injection of IL-1 beta (100 ng/kg) produced an immediate and significant increase in the noradrenaline levels in the spleen. | Norepinephrine | interleukin 1 beta | Rattus norvegicus |
| 5 | An intracerebroventricular (ICV) injection of a corticotropin-releasing factor (CRF) antagonist (alpha-helical CRF9-41, 30 micrograms) significantly attenuated the IL-1 beta-induced increase in the noradrenaline release. | Norepinephrine | interleukin 1 beta | Rattus norvegicus |
| 6 | These results suggest that the intraperitoneal injection of IL-1 beta facilitates noradrenaline release in the spleen through activation of the sympathetic nerve, and the increased sympathetic activity is, at least in part, due to the excitation of neurons containing CRF in the brain. | Norepinephrine | interleukin 1 beta | Rattus norvegicus |