Title : Role of bound GDP in the stability of the rho A-rho GDI complex purified from neutrophil cytosol.

Pub. Date : 1994 Nov 30

PMID : 7999019






6 Functional Relationships(s)
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1 Role of bound GDP in the stability of the rho A-rho GDI complex purified from neutrophil cytosol. Guanosine Diphosphate ras homolog family member A Bos taurus
2 The rho A-rho GDI complex purified from bovine neutrophil cytosol was found to contain GDP as the only bound nucleotide at a ratio of 1 mol of GDP per mol of complex. Guanosine Diphosphate ras homolog family member A Bos taurus
3 The rho A-rho GDI complex purified from bovine neutrophil cytosol was found to contain GDP as the only bound nucleotide at a ratio of 1 mol of GDP per mol of complex. Guanosine Diphosphate ras homolog family member A Bos taurus
4 Upon dephosphorylation of bound GDP by apyrase, the rho A component of the complex was prone to proteolytic cleavage. Guanosine Diphosphate ras homolog family member A Bos taurus
5 These data suggest that rho A liganded by GDP in the rho A-rho GDI complex is maintained in a conformation that escapes action of proteases. Guanosine Diphosphate ras homolog family member A Bos taurus
6 These data suggest that rho A liganded by GDP in the rho A-rho GDI complex is maintained in a conformation that escapes action of proteases. Guanosine Diphosphate ras homolog family member A Bos taurus