Title : Pharmacological actions of l-deprenyl (selegiline) and other selective monoamine oxidase B inhibitors.

Pub. Date : 1994 Dec

PMID : 7995014






1 Functional Relationships(s)
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1 Although not all features of its antiParkinson action are known, studies that used brains obtained at autopsy from patients who took l-deprenyl show that the selective inhibition of MAO-B with a concomitant increase of phenylethylamine and dopamine, but not of serotonin or noradrenaline, in the basal ganglia may be responsible for its mode of action. Norepinephrine monoamine oxidase B Homo sapiens