Title : A possible role of sphingosine in induction of apoptosis by tumor necrosis factor-alpha in human neutrophils.

Pub. Date : 1994 Dec 5

PMID : 7988686






3 Functional Relationships(s)
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1 Treatment of human neutrophils with tumor necrosis factor-alpha (TNF-alpha) resulted in an increase in concentration of ceramide and its catabolite, sphingosine. Ceramides tumor necrosis factor Homo sapiens
2 Treatment of human neutrophils with tumor necrosis factor-alpha (TNF-alpha) resulted in an increase in concentration of ceramide and its catabolite, sphingosine. Ceramides tumor necrosis factor Homo sapiens
3 These results indicate that sphingosine deacylated from ceramide may be an endogenous modulator mediating apoptotic signals by TNF-alpha in neutrophils. Ceramides tumor necrosis factor Homo sapiens