Title : A mutant form of the Ran/TC4 protein disrupts nuclear function in Xenopus laevis egg extracts by inhibiting the RCC1 protein, a regulator of chromosome condensation.

Pub. Date : 1994 Dec 1

PMID : 7988569






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The addition of a bacterially expressed mutant form of Ran (T24N-Ran), which was predicted to be primarily in the GDP-bound state, profoundly disrupted nuclear assembly and DNA replication in extracts. Guanosine Diphosphate ran GTP-binding protein Xenopus laevis
2 The addition of a bacterially expressed mutant form of Ran (T24N-Ran), which was predicted to be primarily in the GDP-bound state, profoundly disrupted nuclear assembly and DNA replication in extracts. Guanosine Diphosphate ran GTP-binding protein Xenopus laevis