Pub. Date : 1994 May
PMID : 7961601
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The hydration of Ras p21 in solution during GTP hydrolysis based on solution X-ray scattering profile. | Guanosine Triphosphate | H3 histone pseudogene 16 | Homo sapiens |
| 2 | In the presence of GDP, the radius of gyration, Rg, determined for wild type ras p21 was 16.89 +/- 0.01 A, while the wild type ras p21 bound to the GTP analogue GDPNHP (5"-guanyl imido diphosphate beta-gamma-imidoguanosine 5"-triphosphate) showed an Rg value of 17.46 +/- 0.01 A, which is 3.3% larger. | Guanosine Triphosphate | H3 histone pseudogene 16 | Homo sapiens |
| 3 | The result shows that ras p21 expands upon GTP binding. | Guanosine Triphosphate | H3 histone pseudogene 16 | Homo sapiens |
| 4 | The scattering profiles were analyzed by simulation of hydrated ras p21, based on the crystal atomic coordinates, and it was concluded that the ras p21 molecule incorporates 20% more bulk water upon GTP binding. | Guanosine Triphosphate | H3 histone pseudogene 16 | Homo sapiens |