Pub. Date : 1994 Nov 15
PMID : 7954398
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Relationship between the structure of taxol and other taxanes on induction of tumor necrosis factor-alpha gene expression and cytotoxicity. | Paclitaxel | tumor necrosis factor | Homo sapiens |
| 2 | Structure-activity studies using taxol and related taxanes have been done to determine the relationship between the effects of taxol on TNF-alpha gene expression and its cytotoxic and microtubule-stabilizing activities. | Paclitaxel | tumor necrosis factor | Homo sapiens |
| 3 | Structure-activity studies using taxol and related taxanes have been done to determine the relationship between the effects of taxol on TNF-alpha gene expression and its cytotoxic and microtubule-stabilizing activities. | Paclitaxel | tumor necrosis factor | Homo sapiens |
| 4 | Using Northern blot analysis, it was found that changes in the structure of taxol that did not alter cytotoxicity did prevent the induction of TNF-alpha gene expression. | Paclitaxel | tumor necrosis factor | Homo sapiens |
| 5 | The data presented in this paper demonstrate that the effects of taxol on TNF-alpha gene expression are distinct from its known cytotoxic properties. | Paclitaxel | tumor necrosis factor | Homo sapiens |