Title : In vivo osmoregulation of Na/myo-inositol cotransporter mRNA in rat kidney medulla.

Pub. Date : 1994 Jul

PMID : 7948784






2 Functional Relationships(s)
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1 myo-Inositol, a major compatible osmolyte in renal medulla, is accumulated in kidney-derived epithelial cells cultured in hypertonic media via Na/myoinositol cotransporter (SMIT). Inositol solute carrier family 5 member 3 Rattus norvegicus
2 These results indicate that there is osmoregulatory SMIT in the outer and inner medulla of the kidney and that myo-inositol accumulation in this region is probably due to the increased expression of the SMIT gene. Inositol solute carrier family 5 member 3 Rattus norvegicus