Title : Effect of moclobemide on rat brain monoamine oxidase A and B: comparison with harmaline and clorgyline.

Pub. Date : 1994 Jul

PMID : 7938567






2 Functional Relationships(s)
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1 Effects of moclobemide (12.5, 25 and 50 mg/kg), harmaline (10 mg/kg) and clorgyline (10 mg/kg) on monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B) were examined ex vivo by a fluorometric method with tyramine (T) and phenylethylamine (PEA) as substrates. Clorgyline monoamine oxidase A Rattus norvegicus
2 Clorgyline was the most potent of the three drug tested for MAO-A inhibition. Clorgyline monoamine oxidase A Rattus norvegicus