Pub. Date : 1994
PMID : 7931219
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The response to administration of the specific monoamine oxidase A (MAO-A) blocker clorgyline was investigated in adult male Sprague-Dawley rats which were adrenalectomized four days prior to treatment or were additionally sympathectomized as newborns by injection of 6-hydroxydopamine. | Clorgyline | monoamine oxidase A | Rattus norvegicus |
2 | The response to administration of the specific monoamine oxidase A (MAO-A) blocker clorgyline was investigated in adult male Sprague-Dawley rats which were adrenalectomized four days prior to treatment or were additionally sympathectomized as newborns by injection of 6-hydroxydopamine. | Clorgyline | monoamine oxidase A | Rattus norvegicus |
3 | The results are in line with the hypothesis that preservation from oxidation of both MAO-A substrates, noradrenaline and serotonin, upon clorgyline administration contributes to the observed increase in melatonin biosynthesis thought to be associated with the anti-depressant effects of MAO inhibition. | Clorgyline | monoamine oxidase A | Rattus norvegicus |
4 | The results are in line with the hypothesis that preservation from oxidation of both MAO-A substrates, noradrenaline and serotonin, upon clorgyline administration contributes to the observed increase in melatonin biosynthesis thought to be associated with the anti-depressant effects of MAO inhibition. | Clorgyline | monoamine oxidase A | Rattus norvegicus |