Pub. Date : 1994 Sep 1
PMID : 7925377
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In a screen, designed for the selection of mutants with reduced glycolytic flux we obtained isolates which were shown by complementation of the cloned wild-type gene to be allelic to the glucose repression mutants grr1/cat80/cot2 previously described. | Glucose | SCF ubiquitin ligase complex subunit GRR1 | Saccharomyces cerevisiae S288C |
| 2 | In a screen, designed for the selection of mutants with reduced glycolytic flux we obtained isolates which were shown by complementation of the cloned wild-type gene to be allelic to the glucose repression mutants grr1/cat80/cot2 previously described. | Glucose | SCF ubiquitin ligase complex subunit GRR1 | Saccharomyces cerevisiae S288C |
| 3 | We demonstrate that the grr1 lesion lead to a concentration-dependent decrease in glycolytic flux on glucose. | Glucose | SCF ubiquitin ligase complex subunit GRR1 | Saccharomyces cerevisiae S288C |
| 4 | We suggest that Grr1, a putative cytoplasmic protein, has a central function in the sensing of nutritional conditions for a variety of unrelated substances, and that relief from glucose repression may be a corollary of this defect in sensing. | Glucose | SCF ubiquitin ligase complex subunit GRR1 | Saccharomyces cerevisiae S288C |