Pub. Date : 1994 Sep
PMID : 7923598
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Mutational activation of the K-ras gene was found at a high frequency in both the B[a]P- and DMN-induced C3A lung tumors. | Dimethylnitrosamine | Kirsten rat sarcoma viral oncogene homolog | Mus musculus |
| 2 | K-ras oncogenes were found on the allele inherited from the susceptible A/J parent in 14/16 of DMN-induced tumors and 15/17 of B[a]P-induced tumors from C3A mice. | Dimethylnitrosamine | Kirsten rat sarcoma viral oncogene homolog | Mus musculus |
| 3 | Furthermore, the K-ras mRNA transcribed from the A/J allele was 5-20 times more than C3H K-ras transcripts in 10/10 DMN-induced and 10/10 B[a]P-induced C3A lung tumors. | Dimethylnitrosamine | Kirsten rat sarcoma viral oncogene homolog | Mus musculus |
| 4 | Furthermore, the K-ras mRNA transcribed from the A/J allele was 5-20 times more than C3H K-ras transcripts in 10/10 DMN-induced and 10/10 B[a]P-induced C3A lung tumors. | Dimethylnitrosamine | Kirsten rat sarcoma viral oncogene homolog | Mus musculus |