Pub. Date : 1994 Sep
PMID : 7923576
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The direct effect of nicotine on the expression of receptors for the tumor necrosis factor alpha (TNF alpha) and transforming growth factor beta (TGF beta) and the internalization, intracellular distribution and stability of these growth factors in cervical cancer cell line SiHa was studied. | Nicotine | tumor necrosis factor | Homo sapiens |
2 | The direct effect of nicotine on the expression of receptors for the tumor necrosis factor alpha (TNF alpha) and transforming growth factor beta (TGF beta) and the internalization, intracellular distribution and stability of these growth factors in cervical cancer cell line SiHa was studied. | Nicotine | tumor necrosis factor | Homo sapiens |
3 | Nicotine at 0.1% stabilized and protected from degradation [125I]TNF alpha and [125I]TGF beta internalized by cervical cancer SiHa cell line. | Nicotine | tumor necrosis factor | Homo sapiens |
4 | In the presence of nicotine, both [125I]TNF alpha and [125I]TGF beta were detected in high quantities and in a non-degraded form in the cytoplasm and chromatin during 5 days of incubation. | Nicotine | tumor necrosis factor | Homo sapiens |
5 | An increased intracellular accumulation of [125I]TNF alpha and [125I]TGF beta in cells exposed to nicotine occurred without changes in expression of the cell surface receptors. | Nicotine | tumor necrosis factor | Homo sapiens |