Title : EGF stimulates both cyclooxygenase activity and cell proliferation of cultured guinea pig gastric mucous cells.

Pub. Date : 1994 Jul

PMID : 7921158






2 Functional Relationships(s)
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1 Exposure of the cells to EGF at concentrations which stimulated DNA synthesis caused increases in both prostaglandin (PG) E2 release and cyclooxygenase (COX) enzyme protein synthesis, as evaluated by Western blot analysis. Dinoprostone pro-epidermal growth factor Cavia porcellus
2 These results suggest that such increases in DNA synthesis and PGE2 release may be involved, at least in part, in the mechanism of EGF-induced local regulation of gastric mucosal integrity. Dinoprostone pro-epidermal growth factor Cavia porcellus