Title : Activation of multiple transcription factor genes by tetrahydrocannabinol in rat forebrain.

Pub. Date : 1994 Jun 2

PMID : 7919180






1 Functional Relationships(s)
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1 Twenty minutes after a single THC injection, significant increases in concentration of the mRNAs for C-FOS, C-JUN and ZIF-268 were observed in the cingulate cortex (75, 45 and 37%) and for C-FOS and ZIF-268 in the fronto-parietal cortex (60 and 64%) and caudate-putamen (81 and 32%) while JUN-D mRNA levels were not changed. Dronabinol JunD proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus