Title : Nicotine increases diazepam binding inhibitor (DBI) mRNA in primary cultured neurons.

Pub. Date : 1994 Feb 28

PMID : 7913213






7 Functional Relationships(s)
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1 Nicotine increases diazepam binding inhibitor (DBI) mRNA in primary cultured neurons. Nicotine diazepam binding inhibitor, acyl-CoA binding protein Homo sapiens
2 Nicotine increases diazepam binding inhibitor (DBI) mRNA in primary cultured neurons. Nicotine diazepam binding inhibitor, acyl-CoA binding protein Homo sapiens
3 The effect of nicotine on the expression of diazepam binding inhibitor (DBI) mRNA in primary cultured cerebral cortical neurons was examined using Northern blot analysis. Nicotine diazepam binding inhibitor, acyl-CoA binding protein Homo sapiens
4 The effect of nicotine on the expression of diazepam binding inhibitor (DBI) mRNA in primary cultured cerebral cortical neurons was examined using Northern blot analysis. Nicotine diazepam binding inhibitor, acyl-CoA binding protein Homo sapiens
5 Nicotine exposure (0.001-10 microM) for 24 h increased the DBI mRNA level in a dose-dependent manner, whereas the beta-actin mRNA level showed no change. Nicotine diazepam binding inhibitor, acyl-CoA binding protein Homo sapiens
6 Hexamethonium (100 microM) completely abolished the nicotine-induced increase in DBI mRNA expression. Nicotine diazepam binding inhibitor, acyl-CoA binding protein Homo sapiens
7 These results indicate that nicotine increases the expression of DBI mRNA in cerebral cortical neurons via the activation of nicotinic acetylcholine receptor. Nicotine diazepam binding inhibitor, acyl-CoA binding protein Homo sapiens