Title : Extent of beta 1- and beta 2-receptor occupancy in plasma assesses the antagonist activity of metoprolol, pindolol, and propranolol in the elderly.

Pub. Date : 1993 Dec

PMID : 7912102






2 Functional Relationships(s)
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1 Extent of beta 1- and beta 2-receptor occupancy in plasma assesses the antagonist activity of metoprolol, pindolol, and propranolol in the elderly. Metoprolol potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens
2 The results and conclusions were the following: (a) The extent to which metoprolol, pindolol, and propranolol occupied rabbit lung beta 1- and rat reticulocyte beta 2-adrenoceptors in plasma samples estimated accurately the intensity of beta-receptor antagonism in the patients who did not tolerate physiological and pharmacological tests measuring the degree of beta 1- and beta 2-adrenoceptor blockade. Metoprolol potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens