Title : Origin of D-alanine present in urine of mutant mice lacking D-amino-acid oxidase activity.

Pub. Date : 1993 Oct

PMID : 7901999






3 Functional Relationships(s)
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1 Urine of mutant ddY/DAO- mice lacking D-amino-acid oxidase contained 13 times more D-alanine than that of normal ddY/DAO+ mice. dalbergioidin D-amino acid oxidase Mus musculus
2 In ddY/DAO- mice that were made germ free at birth and reared in a germ-free environment, the quantity of urinary D-alanine was found to be at a low level comparable to that of the normal mice. dalbergioidin D-amino acid oxidase Mus musculus
3 These results indicate that most of the urinary D-alanine of the conventionally reared ddY/DAO- mice is of gastrointestinal bacterial origin. dalbergioidin D-amino acid oxidase Mus musculus