Pub. Date : 1995 Mar 1
PMID : 7887982
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | High-level cytosolic class-3 aldehyde dehydrogenase (ALDH-3)-mediated oxazaphosphorine-specific resistance (> 35-fold as judged by the concentrations of mafosfamide required to effect a 90% cell-kill) was induced in cultured human breast adenocarcinoma MCF-7/0 cells by growing them in the presence of 30 microM catechol for 5 days. | catechol | aldehyde dehydrogenase 3 family member A1 | Homo sapiens |
| 2 | Cellular levels of ALDH-3 activity were also increased when a number of other human tumor cell lines, e.g. breast adenocarcinoma MDA-MB-231, breast carcinoma T-47D and colon carcinoma HCT 116b, were cultured in the presence of catechol. | catechol | aldehyde dehydrogenase 3 family member A1 | Homo sapiens |