Pub. Date : 1994 Oct 20
PMID : 7885069
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Carbon tetrachloride-induced hepatotoxicity, as judged by the leakage of hepatic enzymes into the bloodstream and the disappearance of hepatic microsomal cytochrome P450, was much less severe in old rats than in young-adult rats. | Carbon Tetrachloride | cytochrome P450, family 2, subfamily g, polypeptide 1 | Rattus norvegicus |
| 2 | For example, serum sorbitol dehydrogenase (SDH) activity following carbon tetrachloride administration was 680 mumol/min/l in old rats compared with 1710 mumol/min/l in young-adult rats, and the loss of hepatic cytochrome P450 was 25% of the total amount in old rats compared with 50% of the total in young-adult rats. | Carbon Tetrachloride | cytochrome P450, family 2, subfamily g, polypeptide 1 | Rattus norvegicus |