Title : The effect of alprazolam on serum cortisol and luteinizing hormone pulsatility in normal women and in women with stress-related anovulation.

Pub. Date : 1995 Mar

PMID : 7883836






3 Functional Relationships(s)
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1 Alprazolam, a benzodiazepine derivative, stimulates specific gamma-aminobutyric acidA receptors and has been found to inhibit CRH activity in the brain. Alprazolam corticotropin releasing hormone Homo sapiens
2 To explain this variation in response to alprazolam, we propose that alprazolam accelerates the GnRH pacemaker in SRA women by inhibiting excessive CRH activity, which blocks the GnRH pacemaker in these women. Alprazolam corticotropin releasing hormone Homo sapiens
3 To explain this variation in response to alprazolam, we propose that alprazolam accelerates the GnRH pacemaker in SRA women by inhibiting excessive CRH activity, which blocks the GnRH pacemaker in these women. Alprazolam corticotropin releasing hormone Homo sapiens