Pub. Date : 1994 Sep-Oct
PMID : 7880974
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | TNF-alpha-stimulated synovial fibroblast DNA synthesis and the release of IL-6, IL-8 and PGE2 was inhibited by antagonist monoclonal antibodies against either the p55 or the p75 TNF receptor, although the blockade of the p55 TNF receptor had a more potent effect than inhibition of the p75 TNF receptor alone. | Dinoprostone | TNF receptor superfamily member 1A | Homo sapiens |
| 2 | Similarly, specific monoclonal antibodies, agonistic for either the p55 or p75 TNF receptor stimulated synovial fibroblast DNA synthesis, as well as IL-6, IL-8 and PGE2 release. | Dinoprostone | TNF receptor superfamily member 1A | Homo sapiens |
| 3 | Both p55 and p75 TNF receptors on dermal and gingival fibroblasts were also involved in TNF-alpha-mediated DNA synthesis and IL-6, IL-8 and PGE2 release, although differences in the levels of DNA synthesis and release of inflammatory cytokines and PGE2 were observed between the three fibroblast types. | Dinoprostone | TNF receptor superfamily member 1A | Homo sapiens |
| 4 | Both p55 and p75 TNF receptors on dermal and gingival fibroblasts were also involved in TNF-alpha-mediated DNA synthesis and IL-6, IL-8 and PGE2 release, although differences in the levels of DNA synthesis and release of inflammatory cytokines and PGE2 were observed between the three fibroblast types. | Dinoprostone | TNF receptor superfamily member 1A | Homo sapiens |