Title : Growth hormone stimulates the tyrosine phosphorylation of the insulin receptor substrate-1 and its association with phosphatidylinositol 3-kinase in primary adipocytes.

Pub. Date : 1995 Feb 24

PMID : 7876077






4 Functional Relationships(s)
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1 Growth hormone stimulates the tyrosine phosphorylation of the insulin receptor substrate-1 and its association with phosphatidylinositol 3-kinase in primary adipocytes. Tyrosine gonadotropin releasing hormone receptor Rattus norvegicus
2 Here we show that IRS-1 is tyrosine-phosphorylated in a time- and dose-dependent manner in response to GH in primary rat adipocytes. Tyrosine gonadotropin releasing hormone receptor Rattus norvegicus
3 Our data suggest that GH-induced tyrosine phosphorylation of IRS-1 and the subsequent docking of PI 3-kinase are important postreceptor events in GH action. Tyrosine gonadotropin releasing hormone receptor Rattus norvegicus
4 Our data suggest that GH-induced tyrosine phosphorylation of IRS-1 and the subsequent docking of PI 3-kinase are important postreceptor events in GH action. Tyrosine gonadotropin releasing hormone receptor Rattus norvegicus