Title : Differential regulation by anti-tumor-promoting 12-deoxyphorbol-13-phenylacetate reveals distinct roles of the classical and novel protein kinase C isozymes in biological responses of primary mouse keratinocytes.

Pub. Date : 1995 Feb

PMID : 7870033






1 Functional Relationships(s)
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1 As was the case with translocation, dPP down-regulated the novel PKC isozymes (delta, epsilon, and eta) with 2 orders of magnitude higher potency (ED50, about 1-2 nM), compared with PKC-alpha (ED50, about 100 nM). 12-deoxyphorbolphenylacetate endothelin receptor type A Mus musculus