Title : Inhibition of nitric oxide synthesis increases the secretion of endothelin-1 in vivo and in cultured endothelial cells.

Pub. Date : 1994 Nov

PMID : 7867388






3 Functional Relationships(s)
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1 Inhibition of nitric oxide synthesis increases the secretion of endothelin-1 in vivo and in cultured endothelial cells. Nitric Oxide endothelin 1 Canis lupus familiaris
2 The aim of this study is to investigate the effects of nitric oxide, formed from L-arginine, on the production of endothelin-1 in vivo and in cultured endothelial cells. Nitric Oxide endothelin 1 Canis lupus familiaris
3 These findings indicate that endogenous nitric oxide is an inhibitory modulator of hypoxic pulmonary vasoconstriction and that nitric oxide inhibits the production of endothelin-1 in vivo and in cultured vascular endothelial cells. Nitric Oxide endothelin 1 Canis lupus familiaris