Title : Three different regulatory mechanisms enable yeast hexose transporter (HXT) genes to be induced by different levels of glucose.

Pub. Date : 1995 Mar

PMID : 7862149






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 GRR1 seems to encode a positive regulator of HXT expression, since grr1 mutants are defective in glucose induction of all four HXT genes. Glucose SCF ubiquitin ligase complex subunit GRR1 Saccharomyces cerevisiae S288C
2 GRR1 seems to encode a positive regulator of HXT expression, since grr1 mutants are defective in glucose induction of all four HXT genes. Glucose SCF ubiquitin ligase complex subunit GRR1 Saccharomyces cerevisiae S288C
3 Mutations in RGT1 suppress the defect in HXT expression caused by grr1 mutations, leading us to propose that glucose induces HXT expression by activating Grr1p, which inhibits the function of the Rgt1p repressor. Glucose SCF ubiquitin ligase complex subunit GRR1 Saccharomyces cerevisiae S288C
4 Mutations in RGT1 suppress the defect in HXT expression caused by grr1 mutations, leading us to propose that glucose induces HXT expression by activating Grr1p, which inhibits the function of the Rgt1p repressor. Glucose SCF ubiquitin ligase complex subunit GRR1 Saccharomyces cerevisiae S288C