Title : Metabolic activation of the N-hydroxy derivative of the carcinogen 4-aminobiphenyl by human tissue sulfotransferases.

Pub. Date : 1995 Feb

PMID : 7859374






1 Functional Relationships(s)
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1 N-OH-ABP sulfotransferase activity was highly sensitive to inhibition by a selective TS-PST inhibitor, 2,6-dichloro-4-nitrophenol (IC50 = 0.7 microM), and by p-nitrophenol, but was unaffected by competitive inhibitors of TL-PST (dopamine) or DHEA-ST (DHEA, DHEA-sulfate). 2,6-dichloro-4-nitrophenol sulfotransferase family 2A member 1 Homo sapiens