Title : Pathways of heat shock protein 28 phosphorylation by TNF in human fibroblasts.

Pub. Date : 1994 Oct

PMID : 7858064






1 Functional Relationships(s)
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1 Treatment of FS-4 cells with sodium arsenite led to a very strong increase in the phosphorylation of Hsp28 demonstrable after 5 min and persisting for at least 4 h. Tyrosine phosphorylation of pp42 and pp44 MAP kinases was increased by TNF treatment, whereas arsenite produced a modest increase in tyrosine phosphorylation of pp44 while decreasing that of pp42 MAP kinase. sodium arsenite tumor necrosis factor Homo sapiens