Title : Molecular correlation between in vitro and in vivo activity of beta-lactam and beta-lactamase inhibitor combinations against methicillin-resistant Staphylococcus aureus.

Pub. Date : 1995 Feb

PMID : 7844469






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 For beta-lactamase-negative strains this correlated with an increased binding affinity of cefoperazone plus sulbactam to PBP2a and PBP4. Sulbactam beta-lactamase Staphylococcus aureus
2 The improved efficacy of cefoperazone plus sulbactam versus cefoperazone with a beta-lactamase producing strain was closely related to cefoperazone hydrolysis by beta-lactamase that was inhibited by sulbactam. Sulbactam beta-lactamase Staphylococcus aureus
3 The improved efficacy of cefoperazone plus sulbactam versus cefoperazone with a beta-lactamase producing strain was closely related to cefoperazone hydrolysis by beta-lactamase that was inhibited by sulbactam. Sulbactam beta-lactamase Staphylococcus aureus
4 The improved efficacy of cefoperazone plus sulbactam versus cefoperazone with a beta-lactamase producing strain was closely related to cefoperazone hydrolysis by beta-lactamase that was inhibited by sulbactam. Sulbactam beta-lactamase Staphylococcus aureus