Title : Behavioral effects of trazodone in Alzheimer's disease.

Pub. Date : 1994 Dec

PMID : 7814348






2 Functional Relationships(s)
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1 BACKGROUND: Central serotonin depletion may contribute to the anxiety, restlessness, irritability, and affective disturbance seen in a variety of psychiatric conditions, particularly dementia of the Alzheimer"s type (DAT) in which brain concentrations of both 5-hydroxytryptamine (5-HT) and its 5-hydroxyindoleacetic acid (5-HIAA) metabolite are reduced. Hydroxyindoleacetic Acid solute carrier family 6 member 3 Homo sapiens
2 BACKGROUND: Central serotonin depletion may contribute to the anxiety, restlessness, irritability, and affective disturbance seen in a variety of psychiatric conditions, particularly dementia of the Alzheimer"s type (DAT) in which brain concentrations of both 5-hydroxytryptamine (5-HT) and its 5-hydroxyindoleacetic acid (5-HIAA) metabolite are reduced. Hydroxyindoleacetic Acid solute carrier family 6 member 3 Homo sapiens