Title : Activin and inhibin have opposite effects on steroid 5 alpha-reductase activity in genital skin fibroblasts.

Pub. Date : 1995 Jan

PMID : 7796940






2 Functional Relationships(s)
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1 In contrast, exposure of cells to an androgen (10(-7) M) and TGF-beta (2 x 10(-10) M) led to synergistic effects on 5 alpha R activity (control 1.5 +/- 0.1%, DHT 2.6 +/- 0.2% TGF-beta 1 4.8 +/- 0.5, TGF-beta 1 + DHT 9.2 +/- 1.2%). Dihydrotestosterone transforming growth factor beta 1 Homo sapiens
2 In contrast, exposure of cells to an androgen (10(-7) M) and TGF-beta (2 x 10(-10) M) led to synergistic effects on 5 alpha R activity (control 1.5 +/- 0.1%, DHT 2.6 +/- 0.2% TGF-beta 1 4.8 +/- 0.5, TGF-beta 1 + DHT 9.2 +/- 1.2%). Dihydrotestosterone transforming growth factor beta 1 Homo sapiens