Title : Cholecystokinin in the control of gastric acid and plasma gastrin and somatostatin secretion in healthy subjects and duodenal ulcer patients before and after eradication of Helicobacter pylori.

Pub. Date : 1994 Dec

PMID : 7787215






3 Functional Relationships(s)
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1 Studies were carried out without or with the pretreatment with placebo or loxiglumide, a specific antagonist of type A CCK receptors. loxiglumide cholecystokinin Homo sapiens
2 The pretreatment with loxiglumide resulted in further increase both in gastric acid secretion and plasma gastrin and CCK, while somatostatin level was significantly reduced. loxiglumide cholecystokinin Homo sapiens
3 Administration of loxiglumide resulted in a significant increase in plasma gastrin and CCK responses to GRP, whereas plasma somatostatin was not significantly altered. loxiglumide cholecystokinin Homo sapiens