Title : Regulation of osteopontin expression in osteoblasts.

Pub. Date : 1995 Apr 21

PMID : 7785896






1 Functional Relationships(s)
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1 Expression of OPN mRNA is upregulated by growth and differentiation factors (PDGF, EGF, TGF-beta and BMP-7/OP-1) and by mechanical stress, which promote bone formation, as well as by osteotropic hormones (retinoic acid and vitamin D3), which can promote bone resorption and remodelling. Cholecalciferol secreted phosphoprotein 1 Rattus norvegicus