Pub. Date : 1995 Feb 14
PMID : 7768285
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Dynorphin A-(1-13) potently improves scopolamine-induced impairment of passive avoidance response in mice. | Scopolamine | prodynorphin | Mus musculus |
| 2 | The effects of intracerebroventricular administration of dynorphin A-(1-13) on scopolamine-induced amnesia were investigated in mice by using a step-down type passive avoidance task. | Scopolamine | prodynorphin | Mus musculus |
| 3 | Dynorphin A-(1-13)(1 microgram) given 15 min before training and retention tests but not immediately after training significantly improved the scopolamine (1 mg/kg)-induced shortening of step-down latency of the passive avoidance response, indicating antiamnesic effects of dynorphin A-(1-13) (1 microgram). | Scopolamine | prodynorphin | Mus musculus |
| 4 | Dynorphin A-(1-13)(1 microgram) given 15 min before training and retention tests but not immediately after training significantly improved the scopolamine (1 mg/kg)-induced shortening of step-down latency of the passive avoidance response, indicating antiamnesic effects of dynorphin A-(1-13) (1 microgram). | Scopolamine | prodynorphin | Mus musculus |