Title : The immature thymocyte is protected from N-methylnitrosourea-induced lymphoma by the human MGMT-CD2 transgene.

Pub. Date : 1995 May

PMID : 7767963






3 Functional Relationships(s)
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1 Since the main phenotype of MNU induced lymphomas in these mice, CD4+CD8+J11d+, is also the cell phenotype which expresses the MGMT-CD2 transgene at high levels, it appears that MGMT-induced protection has occurred in the cell target for MNU induced transformation. Methylnitrosourea O-6-methylguanine-DNA methyltransferase Mus musculus
2 Since the main phenotype of MNU induced lymphomas in these mice, CD4+CD8+J11d+, is also the cell phenotype which expresses the MGMT-CD2 transgene at high levels, it appears that MGMT-induced protection has occurred in the cell target for MNU induced transformation. Methylnitrosourea O-6-methylguanine-DNA methyltransferase Mus musculus
3 Since the main phenotype of MNU induced lymphomas in these mice, CD4+CD8+J11d+, is also the cell phenotype which expresses the MGMT-CD2 transgene at high levels, it appears that MGMT-induced protection has occurred in the cell target for MNU induced transformation. Methylnitrosourea O-6-methylguanine-DNA methyltransferase Mus musculus