Pub. Date : 1995 Feb
PMID : 7756676
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cyclosporin A (CSA) (3 microM), verapamil (10 microM) and S9788 (5 microM) partially reversed the resistance to doxorubicin after a 48 h co-incubation (followed by a 24 h post-incubation for the S9788). | Doxorubicin | ERCC excision repair 8, CSA ubiquitin ligase complex subunit | Homo sapiens |
| 2 | In conclusion this MTC cell line exhibited over-expression of the MDR1 gene and its resistance to doxorubicin can be partially reversed by CSA, verapamil and S9788. | Doxorubicin | ERCC excision repair 8, CSA ubiquitin ligase complex subunit | Homo sapiens |