Title : CYP3A4 and CYP2A6 activities marked by the metabolism of lignocaine and coumarin in patients with liver and kidney diseases and epileptic patients.

Pub. Date : 1995 Jan

PMID : 7756103






1 Functional Relationships(s)
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1 The in vitro hepatic metabolism of lignocaine to monoethylglycinexylide (MEGX) is mediated by CYP3A4 and that of coumarin to 7-hydroxycoumarin (7OHC) by CYP2A6. 7-hydroxycoumarin cytochrome P450 family 2 subfamily A member 6 Homo sapiens