Title : Mammary tumor suppression by transforming growth factor beta 1 transgene expression.

Pub. Date : 1995 May 9

PMID : 7753792






2 Functional Relationships(s)
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1 We report that in crossbreeding experiments involving the production of mice carrying both the MMTV-TGF-beta 1 and MMTV-TGF-alpha transgenes, there is marked suppression of mammary tumor formation and that MMTV-TGF-beta 1 transgenic mice are resistant to 7,12-dimethylbenz[a]anthracene-induced mammary tumor formation. 7,12-dimethylbenz transforming growth factor beta 1 Homo sapiens
2 We report that in crossbreeding experiments involving the production of mice carrying both the MMTV-TGF-beta 1 and MMTV-TGF-alpha transgenes, there is marked suppression of mammary tumor formation and that MMTV-TGF-beta 1 transgenic mice are resistant to 7,12-dimethylbenz[a]anthracene-induced mammary tumor formation. 7,12-dimethylbenz transforming growth factor beta 1 Homo sapiens