Title : The reversibility of airway obstruction to an inhaled beta 2-adrenergic agent is less satisfactory after methacholine testing in asthmatic subjects.

Pub. Date : 1995 May

PMID : 7750333






3 Functional Relationships(s)
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1 The reversibility of airway obstruction to an inhaled beta 2-adrenergic agent is less satisfactory after methacholine testing in asthmatic subjects. Methacholine Chloride potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens
2 AIMS: The aim of this work was to compare the response to an inhaled beta 2-adrenergic agent in two situations: (1) spontaneous airway obstruction in asthmatic subjects who had withheld treatment with the medication for more than 12 hs; and (2) after methacholine-induced airway obstruction once airway caliber had recovered to the premethacholine test value. Methacholine Chloride potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens
3 CONCLUSION: After a methacholine test, the reversibility of an inhaled beta 2 agent is not significantly different from a placebo and is less satisfactory than in a situation of spontaneous airway obstruction. Methacholine Chloride potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens