Pub. Date : 1995 Jun 14
PMID : 7750161
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Induction of Cyp1a-1 and Cyp1a-2 gene expression by a reconstituted mixture of polynuclear aromatic hydrocarbons in B6C3F1 mice. | Polycyclic Aromatic Hydrocarbons | cytochrome P450, family 1, subfamily a, polypeptide 1 | Mus musculus |
| 2 | The potential non-additive interactions of polynuclear aromatic hydrocarbon (PAH) mixtures as inducers of Cyp1a-1 and Cyp1a-2 gene expression were investigated in B6C3F1 mice using a reconstituted PAH mixture. | Polycyclic Aromatic Hydrocarbons | cytochrome P450, family 1, subfamily a, polypeptide 1 | Mus musculus |
| 3 | The > or = 4-ring PAH fraction and reconstituted mixture induced hepatic microsomal ethoxyresorufin O-deethylase (EROD) activity and Cyp1a-1 mRNA levels, whereas the 2- and 3-ring PAHs were only weakly active. | Polycyclic Aromatic Hydrocarbons | cytochrome P450, family 1, subfamily a, polypeptide 1 | Mus musculus |