Pub. Date : 1995 Apr
PMID : 7749861
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Synthetic analogues of the antithrombin III-binding pentasaccharide sequence of heparin. | pentasaccharide | serpin family C member 1 | Rattus norvegicus |
| 2 | The synthetic pentasaccharide Org 31540/SR 90107A represents the antithrombin III (ATIII) binding region of heparin and accelerates the ATIII-mediated inhibition of coagulation factor Xa. | pentasaccharide | serpin family C member 1 | Rattus norvegicus |
| 3 | The synthetic pentasaccharide Org 31540/SR 90107A represents the antithrombin III (ATIII) binding region of heparin and accelerates the ATIII-mediated inhibition of coagulation factor Xa. | pentasaccharide | serpin family C member 1 | Rattus norvegicus |
| 4 | The synthetic pentasaccharide Org 31540/SR 90107A represents the antithrombin III (ATIII) binding region of heparin and accelerates the ATIII-mediated inhibition of coagulation factor Xa. | pentasaccharide | serpin family C member 1 | Rattus norvegicus |
| 5 | After administration of a low dose (100 nmol/kg body wt IV), each pentasaccharide showed a characteristic plasma half-life varying from a minimum of 0.3 hour for pentasaccharides with low affinity for ATIII to 10.9 hours for pentasaccharides with high affinity for the protein. | pentasaccharide | serpin family C member 1 | Rattus norvegicus |
| 6 | The relation between Kd values and plasma half-lives could be explained by assuming rapid clearance of free and coclearance of ATIII-bound pentasaccharide with the protein. | pentasaccharide | serpin family C member 1 | Rattus norvegicus |