Title : Protein-tyrosine phosphatase inhibitors block tumor necrosis factor-dependent activation of the nuclear transcription factor NF-kappa B.

Pub. Date : 1995 May 5

PMID : 7738000






1 Functional Relationships(s)
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1 Since both dithiothreitol and dimercaptopropanol reversed the inhibitory effect of PAO, critical sulfhydryl groups in the PTPase must be involved in NF-kappa B activation by TNF. Dithiothreitol tumor necrosis factor Homo sapiens