Title : Intracoronary infusion of bradykinin: effects on noradrenaline overflow following reperfusion of ischemic myocardium in the anesthetized dog.

Pub. Date : 1994

PMID : 7721230






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Intracoronary infusion of bradykinin: effects on noradrenaline overflow following reperfusion of ischemic myocardium in the anesthetized dog. Norepinephrine kininogen 1 Canis lupus familiaris
2 OBJECTIVE: The aim of this study was to investigate the effects of intracoronary bradykinin (BK) infusion on noradrenaline release and ventricular arrhythmias induced by coronary occlusion and reperfusion in the anesthetized dog. Norepinephrine kininogen 1 Canis lupus familiaris
3 OBJECTIVE: The aim of this study was to investigate the effects of intracoronary bradykinin (BK) infusion on noradrenaline release and ventricular arrhythmias induced by coronary occlusion and reperfusion in the anesthetized dog. Norepinephrine kininogen 1 Canis lupus familiaris
4 RESULTS: BK significantly reduced the amount of noradrenaline released at reperfusion by ischemic myocardium (from 82.1 +/- 31.7 to 11.9 +/- 9.6 ng.min-1), as well as plasma creatine kinase activity at 30 min of reperfusion. Norepinephrine kininogen 1 Canis lupus familiaris
5 CONCLUSION: This suggests that the protective effect of bradykinin against reperfusion-induced sustained ventricular tachycardia could be associated with a reduction in cardiac noradrenaline release. Norepinephrine kininogen 1 Canis lupus familiaris